Title:Gold Nanoparticles as Targeted Delivery Systems and Theranostic Agents in Cancer TherapyĪuthor(s): Alexandra Mioc, Marius Mioc, Roxana Ghiulai*, Mirela Voicu*, Roxana Racoviceanu, Cristina Trandafirescu, Cristina Dehelean, Dorina Coricovac and Codruta Soica Keywords: Gold nanoparticles, targeted delivery, theranostic, cancer therapy, magnetic resonance angiography, Have pointed out data regarding the bioaccumulation and cytotoxicity of gold nanoparticles, but it hasīeen emphasized that size, dose, surface charge, sex and especially administration routes are very important Vitro anti-angiogenic, anti-proliferative and pro-apoptotic effects on various cell lines, such as humanĬervix, human breast, human lung, human prostate and murine melanoma cancer cells. Nevertheless, gold nanoparticles are therapeutic agents demonstrating its in Great contributions in the bioimaging field such as radiotherapy, magnetic resonance angiography and Vaccines), theranostics and agents in photothermal therapy. Playing many roles, such as targeted delivery systems (anticancer agents, nucleic acids, biological proteins, This review presents gold nanoparticles as versatile therapeutic agents Various shapes and sizes by a continuously developing set of means, including chemical, physical orĮco-friendly biological methods. Gold nanoparticles are easily synthesizable in Gold nanoparticles are nowadays in the spotlightĭue to their many well-established advantages. To address these problems, targeted nanoscience isĪn emerging field that promises to benefit cancer patients. Toxicity and severe systemic side effects. Cancer is still a leading cause of death worldwide, while most chemotherapies induce nonselective

Iron core shell nanoparticles